David James

Professor of Bioprocess Engineering, Director of the Advanced Biomanufacturing Centre

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To contact David James email d.c.james@sheffield.ac.uk.

I specialise in biopharmaceutical manufacturing. These are predominantly complex recombinant proteins produced by engineered host cells in culture, which are utilised to successfully treat serious diseases as they offer major therapeutic advantages (e.g. high specificity, affinity and biocompatibility) over conventional small molecule drugs. However, they are relatively expensive to make and due to their inherent complexity they pose enormous challenges in their development, production, formulation and storage.

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Catherine Biggs

Professor of Environmental Engineering

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To contact Catherine Biggs email c.biggs@sheffield.ac.uk.

Some of the most urgent global challenges are around the sustainability of water provision. With such as high percentage of the worlds water unusable, for example in oceans, biological methods for desalination can offer natural solutions. The field of water environment brings together such a variety of projects that are able to combine multidisciplinary approaches through specific tools or applications. This means the potential for using process engineering combined with post-genomic, proteomic and synthetic biology can realistically deliver technical advances in water research that can be implemented by water industry.

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Mark Dickman

Professor of Bioanalytical Science and Engineering

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To contact Mark Dickman email m.dickman@sheffield.ac.uk.

My research focuses on the development and application of analytical techniques to study biological systems. In particular, biological mass spectrometry in conjunction with bioseparations have been utilised to study a wide variety of biological systems.

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Robert Falconer

Senior Lecturer and Course Director for MSc Biological and Bioprocess Engineering

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To contact Robert Falconer email r.j.falconer@sheffield.ac.uk.

Protein chemistry is a science that has a lot of unanswered questions. Some of these are fundamental to life and includes basic questions like "how do enzymes catalyze reactions", "how do salts alter protein stability and solubility", "how do proteins and water interact" and many more. In my research group we use analytical techniques like terahertz spectroscopy and microcalorimetry to explore some of these questions. Our strategy is to gather quality experimental observations then challenge the current theories that try to explain these phenomena.

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Jags Pandhal

Lecturer in Bioengineering

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To contact Jags Pandhal email j.pandhal@sheffield.ac.uk.

The combination of environment and biomanufacturing provides new and exciting ways of understanding the world and then translating it for the benefit of mankind.

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Seetharaman Vaidyanathan

Senior Lecturer in Biological & Bioprocess Engineering

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To contact Seetharaman Vaidyanathan email s.vaidyanathan@sheffield.ac.uk.

I am interested in developing biomanufacturing routes that provide environmental (and economic) sustainablility, whether it is for manufacturing high value chemicals or bulk commodities. I am of the opinion that the processes we develop for meeting our needs should leave little or no footprint on our environment that is damaging. Today, a lot of our day-to-day needs are met primarily through our reliance on fossil fuels and petrochemical-based feedstock and processes. Whilst many of these chemical processes are versatile and have spurred the global economy, some of these have come at the expense of increasing damage to our environment.

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Tuck Seng Wong

AMIChemE Lecturer Programme leader – Degree with Employment Experience or Year in Industry

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To contact Tuck Seng Wong email t.wong@sheffield.ac.uk.

Nature has created a stunning array of enzymes and biological systems, capable of performing highly sophisticated functions. I am interested in tracking Nature's molecular footsteps. Through understanding Nature's design secrets, I hope to develop biocatalytic systems that suit industrial needs. My passion for protein engineering is inspired by some of the greatest protein scientists in the world (Prof. Sir Alan R. Fersht, Prof. Frances H. Arnold, and Prof. Ulrich Schwaneberg).

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William Zimmerman

Professor of Biochemical Dynamical Systems

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To contact William Zimmerman email w.zimmerman@sheffield.ac.uk.

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Xiubo Zhao

Lecturer

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To contact Xiubo Zhao email xiubo.zhao@sheffield.ac.uk.

Nature started the evolution of biomolecules from the primitive ones through countless iterations of self-assembly and disassembly and ultimately produced an enormous amount of complex but intriguing biomolecular systems. But why and how? Curiosity drives us to explore the mystery of natural systems. In return, understanding the natural systems gives us knowledge, inspirations and materials which are extremely important and allow us to create valuable artificial systems that are not only extending our existing knowledge but also add bricks to technology development, particularly, in the areas of healthcare and biomedical science.

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Centre Manager

Karen Wood

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To contact Centre Manager email karen.wood@sheffield.ac.uk.

Biomanufacturing research is contributing new tools and techniques that can be applied in fields such as biopharmaceuticals and bioenergy. It is great to be part of a team that is helping to translate that research into 'real world' applications. By maximising the opportunities of linking our core research, with education and training as well as industrial partnerships the Advanced Biomanufacturing Centre will be a key player driving biomanufacturing forwards.

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Alastair Goldman

Professor Alastair Goldman, Dept. Molecular Biology & Biotechnlolgy

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To contact Alastair Goldman email .

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Stuart Wilson

Professor Stuart Wilson, Dept. Molecular Biology and Biotechnology

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To contact Stuart Wilson email .

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